IT1133696B - Acidi 3-benzoil-2-nitrofenil-acetici,loro derivati e composizioni farmaceutiche contenenti tali composti - Google Patents

Acidi 3-benzoil-2-nitrofenil-acetici,loro derivati e composizioni farmaceutiche contenenti tali composti

Info

Publication number
IT1133696B
IT1133696B IT25409/80A IT2540980A IT1133696B IT 1133696 B IT1133696 B IT 1133696B IT 25409/80 A IT25409/80 A IT 25409/80A IT 2540980 A IT2540980 A IT 2540980A IT 1133696 B IT1133696 B IT 1133696B
Authority
IT
Italy
Prior art keywords
nitrophenyl
benzoyl
derivatives
compounds
pharmaceutical compositions
Prior art date
Application number
IT25409/80A
Other languages
English (en)
Italian (it)
Other versions
IT8025409A0 (it
Inventor
David Allan Walsh
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of IT8025409A0 publication Critical patent/IT8025409A0/it
Application granted granted Critical
Publication of IT1133696B publication Critical patent/IT1133696B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT25409/80A 1979-10-18 1980-10-17 Acidi 3-benzoil-2-nitrofenil-acetici,loro derivati e composizioni farmaceutiche contenenti tali composti IT1133696B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/086,195 US4254146A (en) 1979-10-18 1979-10-18 3-Benzoyl-2-nitrophenylacetic acids, metal salts, amides and esters

Publications (2)

Publication Number Publication Date
IT8025409A0 IT8025409A0 (it) 1980-10-17
IT1133696B true IT1133696B (it) 1986-07-09

Family

ID=22196924

Family Applications (1)

Application Number Title Priority Date Filing Date
IT25409/80A IT1133696B (it) 1979-10-18 1980-10-17 Acidi 3-benzoil-2-nitrofenil-acetici,loro derivati e composizioni farmaceutiche contenenti tali composti

Country Status (13)

Country Link
US (1) US4254146A (en])
JP (1) JPS5681540A (en])
AU (1) AU534384B2 (en])
BE (1) BE885700A (en])
CA (1) CA1146964A (en])
CH (1) CH648285A5 (en])
DE (1) DE3038966A1 (en])
FR (1) FR2467840A1 (en])
GB (1) GB2061274B (en])
IL (1) IL61210A (en])
IT (1) IT1133696B (en])
NL (1) NL8005750A (en])
PH (1) PH15693A (en])

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5475034A (en) * 1994-06-06 1995-12-12 Alcon Laboratories, Inc. Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
AR030345A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
AR030346A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes neurodegenerativos de la retina y cabeza de nervio optico
US6646003B2 (en) 2001-04-02 2003-11-11 Alcon, Inc. Method of treating ocular inflammatory and angiogenesis-related disorders of the posterior segment of the eye using an amide derivative of flurbiprofen or ketorolac
WO2003092669A2 (en) * 2002-05-03 2003-11-13 Alcon, Inc. Method of treating vascular endothelial growth factor mediated vascular disorders using amfenac or nepafenac
US20030187072A1 (en) * 2003-02-14 2003-10-02 Kapin Michael A. Method of treating angiogenesis-related disorders
TWI358290B (en) 2004-12-02 2012-02-21 Alcon Inc Topical nepafenac formulations
TW200812575A (en) * 2006-04-28 2008-03-16 Alcon Inc Formulations containing amide derivatives of carboxylic acid NSAIDs for topical administration to the eye
US20080153818A1 (en) * 2006-12-21 2008-06-26 Bingaman David P Methods for preventing inflammation during surgery
US20090105245A1 (en) * 2006-12-21 2009-04-23 Bingaman David P Methods for treating macular edema and ocular angiogenesis using an anti-inflammatory agent and a receptor tyrosine kinase inhibitor
US20080153819A1 (en) * 2006-12-21 2008-06-26 Bingaman David P Methods for treating macular edema and pathologic ocular angiogenesis using a neuroprotective agent and a receptor tyrosine kinase inhibitor
CN116444361A (zh) * 2017-10-11 2023-07-18 浙江瑞博制药有限公司 一种酮基布洛芬通式化合物的六步制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226344A (en]) * 1967-07-31 1971-03-24
CH577461A5 (en]) * 1975-08-13 1976-07-15 Robins Co Inc A H

Also Published As

Publication number Publication date
AU534384B2 (en) 1984-01-26
BE885700A (fr) 1981-02-02
PH15693A (en) 1983-03-11
JPH0222059B2 (en]) 1990-05-17
IL61210A (en) 1985-07-31
FR2467840B1 (en]) 1984-03-30
JPS5681540A (en) 1981-07-03
IL61210A0 (en) 1980-12-31
CA1146964A (en) 1983-05-24
CH648285A5 (fr) 1985-03-15
FR2467840A1 (fr) 1981-04-30
NL8005750A (nl) 1981-04-22
IT8025409A0 (it) 1980-10-17
GB2061274B (en) 1983-10-19
DE3038966A1 (de) 1981-04-30
AU6346280A (en) 1981-04-30
GB2061274A (en) 1981-05-13
US4254146A (en) 1981-03-03
DE3038966C2 (en]) 1989-12-28

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